The occurrence of matriptase C-terminal fragments on the apical and basolateral sides of Madin-Darby canine kidney epithelial cells.

نویسندگان

  • Satoshi Tsuzuki
  • Yuka Miyake
  • Kuniyo Inouye
  • Tohru Fushiki
چکیده

Matriptase is a type II transmembrane serine protease. In the present study, matriptase C-terminal fragments containing the catalytic serine protease domain were found to occur on the apical and basolateral sides of Madin-Darby canine kidney epithelial cells transfected with a cDNA encoding the protease. This suggests that matriptase interacts with various potential substrates when expressed in simple epithelia.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 73 11  شماره 

صفحات  -

تاریخ انتشار 2009